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Colchicine treatment for gout

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Physicians should ensure that patients are suitable candidates for treatment with colchicine capsules and remain alert for signs and symptoms of toxic reactions associated with increased colchicine exposure due to drug interactions.

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Even if colchicine is safe, that doesn t mean that it s effective for gout even if it has been previously found safe and effective for inflammation.

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At toxic doses, colchicine may cause severe diarrhea, generalized vascular damage, and renal damage with hematuria and oliguria.

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The most commonly reported adverse reactions with colchicine are gastrointestinal symptoms, including diarrhea, nausea, vomiting, and abdominal pain.

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If you re taking colchicine to prevent a gout attack and you experience an attack during treatment, call your doctor right away.

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in addition, patients in the icap study likely received excellent counseling about colchicine s side effects and did, in fact, have the benefit of close clinical and biochemical monitoring for toxic effects.

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